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I`ve been asked this kind of topic over and over again. Most of people asking this do not have any updated antivirus or anti spyware solution, so going through the common way is difficult.

If you think persistent spyware is bogging down your computer, Hijackthis may help you to troubleshoot the problem. Hijackthis will examine certain critical areas of the registry and hard drive and list their contents on a log file. Remember; do not remove all these registry entries as u could be deleting some legitimate entries. A good solution is to post the log file to a tech forum and ask for expert opinion.

If nobody responded your query on a tech forum you may try Hijackthis Auto Analyzer for a hint. Paste your hijackthis log file on the form and the system will parse the entry against few databases to determine which entry in your log are OK and which ones are bad! Reboot your computer in safe mode and delete the bad entries via regedit. If your regedit has been disabled by some virus/spyware , copy the code below and paste in Run window . Press enter to reenable your regedit.

REG add HKCU\Software\Microsoft\Windows\CurrentVersion\Policies\System /v DisableRegistryTools /t REG_DWORD /d 0 /f